Very interesting , a lot of usuful knowledge, but become like a reserach paper time to time, at this points it was easy to get distructed
This book presented the rise of antibiotics in a well written and attention catching manner. The intertwining of historical events and their interplay with the discovery process was dynamic and engaging. Well worth reading, right until the end.
At the end of the book the author starts bemoaning the doctors of "the Good ol' days" when they would come to your home and stand by watching over you and holding your hand... while you died horribly of a staph infection! Except that he deliberately leaves out the death part. He then goes on to bemoan the loss of such wonderful things as self medication and homeopathy. Yeah I really wish I could try to figure out what will best cure me, what I want to do is research thousands of drugs and make a rational and informed decision while I am suffering from a fever of 104* or I could just take the "magic water" of homeopathy. So listen to the book but skip the epilouge.
Retired teacher of literature with an interest in religion and in science and in history. I have loved reading for 50 years.
This is the true story of the most important discovery in the history of medicine, and perhaps the most important discovery in the history of man. Prior to the development of anti-bacterial drugs that work INSIDE the body, not just on the surface like antiseptics such as alcohol do, a person with an internal infection was already dead...unless he was one of the few in a million who got lucky. Some scientists believed it possible to create such an internally acting chemical...one that would kill bacteria but not kill the human being infected with the bacteria. Others said such a goal was simply mad.
In labs men of science and medicine laboriously searched for something they were not even sure could possibly exist...and they tried endless examples of chemicals, hundreds of variations...and one day something happened and there was an indication that the dream was not just a fantasy.
Among the fascinating details in this story of world-changing discovery is the tale of the German discovery of an antibacterial agent in the 1930s that saved the life of Winston Churchill in the middle of World War II when Churchill developed a nearly fatal infection. And there is the tale of the scientist sent to prison in Nazi Germany for being "too polite" in refusing a Nobel Prize for his scientific discovery....Hitler had declared that no German would accept a Nobel Prize after a Nobel was awarded to an anti-Nazi peace activist. So when the scientist declined the offer of the Nobel Prize but did so in a letter that the Gestapo thought too polite, the scientist was jailed promptly.
Then there is the tale of the sons of two U.S. presidents....one who died while his dad was president and the other who survived an illness while his dad was president...the two ill sons separated by only a dozen years and by the discovery of effective internal anti-bacterial medicine.
A compelling narrative indeed.
This book might have been too dense to read but I found listening to be enjoyable. I was a bit confused early on by the similar sounding names of the protagonists but continued listening because my hands were messy (I listen in my art studio) and soon the name confusion was a non-issue.
The story is not exactly linear; it jumps between different times and different important figures in the development. I think this aspect of the structure of the story helped make it an interesting listen. It was interesting to start to piece together what was going on in different places. The author allowed the listener to start to make the connections on her own.
I probably finished the book in 2 days.
One of my favorite non-fiction audiobooks. An absolute epic. The description of the book is spot on, if the description piques your interest, the book won't disappoint.
Membre since March 2008.
Top 5 on my list of all time favorite books. If you like history and science this book is for you. Amazing to see how dedicated the men of science are at finding cures for humanity.
Great history in it as well.
Narration is great. Many facts about all the different people in all the different countries working on stopping bacterial infections. Great characterization of all the people. I like how many points are backed up by actual journal entries of the person being talked about.
I loved this amazing book. It vividly describes the difficulties, the frustrations and the serendipity that often precede a major scientific discovery. It brings to life the dedication of medical doctors that work tirelessly (often for decades!) to find ways of curing the awful diseases that plague us. And it makes me ever so grateful to live in the age of antibiotics!
Who would have guessed it was possible to build a fascinating history around chemical labs and medical pathologists? This book does all that and more. It added to my admiration and respect for my grandmothers (and their forebears) who faced the risk, among others, of mortal and incurable diseases every time they entered a hospital to deliver a baby. It made me realize how much we take for granted in modern medicine: the antibiotics that have erased the worries about pneumonia, TB, strep and other infections that were a life and death struggle as recently as the 1930's.
The book fully explains the scientific history behind the discovery of the sulfa drugs by researchers at the Bayer firm in Germany. That took years of dedication and financial support, as well as some lucky hunches. The account keeps its interest by blending in personal stories of people who were cured by the new drugs (e.g., Franklin Roosevelt, Jr.) or otherwise impacted by them (e.g., the head of a "patent medicine" firm in Kentucky that quickly put out an elixir containing the drug that turned out to be poisonous).