Within the first fifteen minutes, I had figured out the vehicle for the plot. From there it was annoying and sometimes agonizing to watch the protagonist's risk-taking (even though his behavior was pretty well-motivated, one of Connelly's strengths). It was too easy to figure out the culprits. Narration also not to my taste--technically fine, but seemed a bit expressionless (maybe fitting for a plot about a workaholic chemist?)
The story was OK. Nothing particularly creative or unpredictable, but decent entertainment while sitting on the Metro. However, the narration stunk. It was filled with drama and sharp intakes of breath in almost every sentence, regardless of the topic of the sentence. It was as if the narrator was told that this was to be a Suspense, and therefore, without consciously reading it, just let the words pass from the page to his mouth. It was distracting and annoying.
It was a refreshing break from James Patterson, Nichols Sparks, etc. It held my interest from beginning to end. I never knew what would happen next to poor Henry. I will definitely read more by Mr. Connelly.